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Creatinine clearance calculator (24-hour urine)

Compares creatinine in a 24-hour urine collection with creatinine in your blood to estimate how much blood your kidneys clear each minute. Type your results in the units on your report and it works out Creatinine Clearance as you type, in your browser.

AI-drafted. Awaiting verificationLast reviewed 2026-10-03Kidneys

From a blood sample taken during the collection.

Type your results above, or fill in the example, to see Creatinine Clearance.

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Educational information, not medical advice. Blood Test Tracker doesn’t diagnose or treat, and it doesn’t replace your clinician. Talk with your clinician before changing medications, supplements or care.

How it’s worked out

The formula

CrCl (mL/min) = [urine creatinine (mg/dL) × 24-hour urine volume (mL)] ÷ [serum creatinine (mg/dL) × collection time (minutes, 1,440 for 24 hours)]; body-size-adjusted CrCl (mL/min/1.73 m²) = CrCl × 1.73 ÷ body surface area (m²)

A worked example

Example numbers, not anyone’s real results, run through the same code as the calculator above.

Example inputs and the result
Urine Creatinine100 mg/dL
24h Urine Volume1,500 mL/24 h
Blood creatinine1 mg/dL
Creatinine Clearance104 mL/min

What Creatinine Clearance tells you

Creatinine is a waste product from muscle that your kidneys remove from the blood. For this test you collect all of your urine for 24 hours and have a blood sample taken close to that time. The lab compares how much creatinine ended up in the urine with how much is in your blood. The result is the volume of blood cleared of creatinine each minute, which gives an estimate of how well your kidneys filter. Some labs print the raw number (mL/min) and others adjust it to a standard body size of 1.73 m² (mL/min/1.73 m²), so check which one your report uses.

Creatinine clearance gives another way to look at kidney filtration (GFR) using your own urine, not just a formula. KDIGO suggests it only when a directly measured GFR is not available and the blood-based eGFR from creatinine plus cystatin C is thought to be inaccurate. The catch is the 24-hour collection, which is easy to get wrong. In a review of 23 studies, KDIGO found that it differed from measured GFR by about 25% on average.

Read the full page on Creatinine Clearance, with what a high or low result can mean.

Usual ranges

The ranges the result above is placed on. Your own lab’s printed range comes first if it gives one.

Sources

The equation

  1. Creatinine Clearance, Urine (test 0020474), ARUP Laboratories
  2. CRCL - Creatinine Clearance, Serum and 24-Hour Urine, Mayo Clinic Laboratories (via the Schneck Medical Center test catalog)
  3. KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease, Kidney International 105(4S):S117-S314 (2024)
3 more sources for the ranges and the explanation
  1. Pediatric Testing Reference Ranges (includes Creatinine Clearance, test 003004), Labcorp
  2. Creatinine clearance test, MedlinePlus (National Library of Medicine)
  3. ABIM Laboratory Test Reference Ranges, American Board of Internal Medicine (2026)

AI-drafted. Awaiting verification. Last reviewed 2026-10-03. The calculator is version 1.0.0 of our code for this equation, tested against published examples. How we build and check these pages.

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