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SHBG by age and sex

What’s typical for SHBG at every adult age, from a U.S. government health survey of 18,165 people, next to the usual ranges labs print.

NHANES 2015–2016, 2017–March 2020 (pre-pandemic), August 2021–August 202318,165 adultsAI-verified against cited sources. Awaiting expert review

What’s typical at one age

Pick a sex and an age to see the spread among U.S. adults like that, and type a result to see where it falls.

U.S. women aged 40–49

1,448 people in NHANES, 2015–2016, 2017–March 2020 (pre-pandemic), August 2021–August 2023.

Women aged 40–49, 1,448 people: median 56.0, middle half 37.9 to 83.1, middle 90% 21.7 to 157 nmol/L. Usual range 24.6 to 122.

Median (half are lower)
56.0 nmol/L
Middle half of people
37.9 to 83.1
Middle 90% of people
21.7 to 157
Usual range a lab prints
24.6 to 122

Shaded: the middle 90% and middle half of people. Dark line: the median. The bracket above: the usual range.

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Across adult life

NHANES describes the US civilian, non-institutionalized population, not a 'healthy' reference group. People with disease, on medication, fasting or not (except fasting-subsample markers), smokers and so on are all included. A percentile says where a value sits among Americans of that sex and age, not whether it is normal.

How SHBG varies with age in the U.S.Shaded: middle 90% and middle 50% of people. Line: the median. nmol/L. Point at any age, or focus the chart and use the arrow keys, to read both sexes in words.

Use the left and right arrow keys to read each age. Shift moves five years.

Reference data derived from CDC/NCHS National Health and Nutrition Examination Survey (NHANES), cycles 2015-2016, 2017-March 2020 (pre-pandemic), August 2021-August 2023. Analysis by bloodtesttracker.com; not endorsed by CDC, NCHS or HHS.

The 25th percentile means a quarter of people in that group had a lower result. In nmol/L. A dash means too few people were measured for the survey to publish that number.

Women

SHBG percentiles for U.S. women by age, in nmol/L, NHANES 2015–2016, 2017–March 2020 (pre-pandemic), August 2021–August 2023
AgePeople2.5th5th10th25thMedian75th90th95th97.5th
18–291,5981417.822.133.852.385.5158198.3233.6
30–391,43018.22125.13654.883.5122.7165.1202.5
40–491,44817.621.727.737.95683.1114.9157190.5
50–591,5511618.523.234.449.874.2100.9126.4148.3
60–691,85817.921.626.536.45480.5103.9124.3148.8
70–791,04820.825.632.543.862.789.1121.2148.2170.1
80+56222.73038.752.976.5110152.8177.5193.1
All adults9,49517.120.525.636.755.583.4120.8158192.5

Men

SHBG percentiles for U.S. men by age, in nmol/L, NHANES 2015–2016, 2017–March 2020 (pre-pandemic), August 2021–August 2023
AgePeople2.5th5th10th25thMedian75th90th95th97.5th
18–291,52610.912.514.419.727.137.450.358.764.2
30–391,22811.41315.920.628.138.752.962.374.7
40–491,23912.5141722.931.641.256.566.577.3
50–591,32913.816.619.92736.849.465.179.498.5
60–691,72817.921.224.932.943.15878.892.2108.7
70–791,08220.823.627.835.948.363.882.598.3112.5
80+53824.428.934.444.759.577.1102.6115.4129.3
All adults8,67012.514.417.724.234.348.565.679.194

About these numbers

  • NHANES describes the US civilian, non-institutionalized population, not a 'healthy' reference group. People with disease, on medication, fasting or not (except fasting-subsample markers), smokers and so on are all included. A percentile says where a value sits among Americans of that sex and age, not whether it is normal.
  • Assays differ between labs and between NHANES cycles. Values from a commercial lab can sit a few percent higher or lower than NHANES for the same blood. Earlier cycles were bridged to the 2021-2023 method with NCHS equations where NCHS recommends it.
  • Age 80 and over is top-coded at 80 in public NHANES files, so the 80+ cell mixes everyone 80 and older.
  • 2021-2023 (cycle L) had a 25.7% exam response rate and no race/income oversampling; NCHS advises caution when combining it with earlier cycles.

Reference data derived from CDC/NCHS National Health and Nutrition Examination Survey (NHANES), cycles 2015-2016, 2017-March 2020 (pre-pandemic), August 2021-August 2023. Analysis by bloodtesttracker.com; not endorsed by CDC, NCHS or HHS.

Centers for Disease Control and Prevention (CDC). National Center for Health Statistics (NCHS). National Health and Nutrition Examination Survey Data. Hyattsville, MD: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, 2015-2016, 2017-March 2020 (pre-pandemic), August 2021-August 2023. https://wwwn.cdc.gov/nchs/nhanes/

How we use survey data

The usual range at every age

The reference range labs print, for each age group. Ranges differ a little between labs, so the range on your own report is the one your result is judged against.

Use the left and right arrow keys to step through the age groups. Every range is also in the table below.

Usual range of SHBG by age, in nmol/L
WhoUsual range
Women, 1–360–190 nmol/L
Women, 4–655–170 nmol/L
Women, 7–935–170 nmol/L
Women, 10–1217–155 nmol/L
Women, 13–1511–120 nmol/L
Women, 16–1719–145 nmol/L
Women, 18–1925–122 nmol/L
Women, 20–4924.6–122 nmol/L
Women, 50+17.3–125 nmol/L
Men, 1–350–180 nmol/L
Men, 4–645–175 nmol/L
Men, 7–928–190 nmol/L
Men, 10–1223–160 nmol/L
Men, 13–1513–140 nmol/L
Men, 16–1710–60 nmol/L
Men, 18–1917–56 nmol/L
Men, 20–4916.5–55.9 nmol/L
Men, 50+19.3–76.4 nmol/L

Sources: ARUP Laboratories, Labcorp