{"id":"tryptase","name":"Tryptase","shortName":"Tryptase","aliases":["Mast Cell Tryptase","Tryptase, Total","Total Tryptase","Tryptase, Serum","Serum Tryptase","Baseline Tryptase","Acute Tryptase","Tryptase Total"],"abbreviations":["MCT","bST"],"loinc":[{"code":"21582-2","primary":true}],"specimen":"serum-or-plasma","units":[{"ucum":"ug/L","display":"µg/L"},{"ucum":"ng/mL","display":"ng/mL"}],"referenceRanges":[{"population":"Adults","low":null,"high":11.4,"unit":"ug/L","unitDisplay":"µg/L","note":"Labs print different upper limits. The test maker's upper limit, the 95th percentile of healthy people, is 11.4 µg/L, and a 2023 German venom allergy guideline and a 2023 review both quote it. ARUP prints 10.9 µg/L or lower, Mayo Clinic Laboratories prints under 11.5 ng/mL, the University of Washington lab prints 0 to 12 ng/mL, and Labcorp prints 2.2 to 13.2 µg/L. Results given in ng/mL are the same numbers as µg/L. A group of mast cell experts (ECNM and AIM) suggests a normal baseline range of 1 to 15 µg/L. The sources read here give one interval for adults and do not split it by age or sex. A baseline sample is taken at least 24 hours after a reaction has ended, and a sample taken within hours of a reaction is expected to run higher. Use the range printed on your own lab report.","sources":[{"title":"Diagnosis and treatment of Hymenoptera venom allergy: S2k Guideline of the German Society of Allergology and Clinical Immunology (DGAKI)","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10580978/","publisher":"Allergologie Select","year":2023},{"title":"Diagnostic Significance of Tryptase for Suspected Mast Cell Disorders","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10742504/","publisher":"Diagnostics (Basel)","year":2023},{"title":"World Allergy Organization Anaphylaxis Guidance 2020","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7607509/","publisher":"World Allergy Organization Journal","year":2020},{"title":"Tryptase (ARUP test 0099173)","url":"https://ltd.aruplab.com/Tests/Pub/0099173","publisher":"ARUP Laboratories"},{"title":"Tryptase, Serum (test ID TRYPT)","url":"https://www.mayocliniclabs.com/test-catalog/overview/81608","publisher":"Mayo Clinic Laboratories"},{"title":"Tryptase Result (UW Medicine Laboratory Test Guide, test TRYPR)","url":"https://testguide.labmed.uw.edu/view/TRYPR?tabs=no","publisher":"University of Washington Department of Laboratory Medicine and Pathology"},{"title":"Tryptase (test 004280)","url":"https://www.labcorp.com/tests/004280/tryptase","publisher":"Labcorp"}]}],"review":{"status":"ai-verified","label":"AI-verified against cited sources. Awaiting expert review","lastReviewed":"2026-10-03"},"summary":"Measures tryptase, a protein mast cells release in allergic reactions. It is checked after a possible severe reaction and to find your usual baseline level.","url":"https://bloodtesttracker.com/markers/tryptase","notice":"Information, not medical advice. Ranges differ between labs, so the range on your own report is the one your result is judged against."}