{"id":"troponin-i","name":"Troponin I (Cardiac, incl. High-Sensitivity)","shortName":"Troponin I","aliases":["Troponin I","TROPONIN I HS","High Sensitivity Troponin I","cTnI","hs-Troponin I","hs-cTnI","hsTnI","Troponin I, Cardiac","Troponina I ultrasensible","Troponin I, High Sensitivity","Troponin I, High Sensitivity, Plasma","Cardiac Troponin I","High-Sensitivity Cardiac Troponin I"],"abbreviations":["cTnI","hs-cTnI","hsTnI","TnI"],"loinc":[{"code":"89579-7","primary":true},{"code":"10839-9","primary":false},{"code":"106906-1","primary":false},{"code":"42757-5","primary":false}],"specimen":"serum-or-plasma","units":[{"ucum":"ng/L","display":"ng/L"},{"ucum":"pg/mL","display":"pg/mL"},{"ucum":"ng/mL","display":"ng/mL"}],"referenceRanges":[{"population":"Men, 18+","low":null,"high":35,"unit":"ng/L","unitDisplay":"ng/L","note":"This is the 99th percentile for men on the Abbott ARCHITECT STAT high-sensitivity assay as labeled in the US (the manufacturer-designated value in the IFCC table). Abbott's Alinity i lists 34.2 ng/L and published studies on the ARCHITECT used 34 ng/L. Every assay has its own limit and results from different assays cannot be compared: Mayo Clinic Laboratories' ECLIA assay lists 20 ng/L or less for men, Beckman Coulter Access lists about 20 ng/L, and published healthy-population limits across platforms range from about 11 to 72 ng/L. The 99th percentile is the upper limit of what the assay sees in healthy people, not a diagnosis. Use the range printed on your own report.","sources":[{"title":"High-Sensitivity Cardiac Troponin I and T Assay Analytical Characteristics Designated by Manufacturer (v072026)","url":"https://ifcc.org/ifcc-education-division/emd-committees/committee-on-clinical-applications-of-cardiac-bio-markers-c-cb/biomarkers-reference-tables/","publisher":"IFCC Committee on Clinical Applications of Cardiac Bio-Markers","year":2026},{"title":"Highly Sensitive Cardiac Troponins: The Evidence Behind Sex-Specific Cutoffs","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7660872/","publisher":"Journal of the American Heart Association","year":2020},{"title":"Fifth Universal Definition of Myocardial Infarction (2026): On behalf of the Joint ESC/ACC/AHA/WHF Task Force for the Universal Definition of Myocardial Infarction","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13523810/","publisher":"Global Heart","year":2026},{"title":"Troponin I, High Sensitivity, Plasma (test HSTNI)","url":"https://www.testcatalog.org/show/HSTNI","publisher":"Mayo Clinic Laboratories"},{"title":"Use of high-sensitivity cardiac troponin in the emergency department: A policy resource and education paper (PREP) from the American College of Emergency Physicians","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10324464/","publisher":"JACEP Open","year":2023}]},{"population":"Women, 18+","low":null,"high":17,"unit":"ng/L","unitDisplay":"ng/L","note":"This is the 99th percentile for women on the Abbott ARCHITECT STAT high-sensitivity assay as labeled in the US (the manufacturer-designated value in the IFCC table). Abbott's Alinity i lists 15.6 ng/L. The 2026 Universal Definition of Myocardial Infarction asks labs to use sex-specific limits because the female limit is lower. Mayo Clinic Laboratories' ECLIA assay lists 15 ng/L or less for women and Beckman Coulter Access lists about 12 ng/L. Older conventional (non-high-sensitivity) tests report in ng/mL and have their own limits. Use the range printed on your own report.","sources":[{"title":"High-Sensitivity Cardiac Troponin I and T Assay Analytical Characteristics Designated by Manufacturer (v072026)","url":"https://ifcc.org/ifcc-education-division/emd-committees/committee-on-clinical-applications-of-cardiac-bio-markers-c-cb/biomarkers-reference-tables/","publisher":"IFCC Committee on Clinical Applications of Cardiac Bio-Markers","year":2026},{"title":"Highly Sensitive Cardiac Troponins: The Evidence Behind Sex-Specific Cutoffs","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7660872/","publisher":"Journal of the American Heart Association","year":2020},{"title":"Fifth Universal Definition of Myocardial Infarction (2026): On behalf of the Joint ESC/ACC/AHA/WHF Task Force for the Universal Definition of Myocardial Infarction","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13523810/","publisher":"Global Heart","year":2026},{"title":"Troponin I, High Sensitivity, Plasma (test HSTNI)","url":"https://www.testcatalog.org/show/HSTNI","publisher":"Mayo Clinic Laboratories"}]}],"review":{"status":"ai-verified","label":"AI-verified against cited sources. Awaiting expert review","lastReviewed":"2026-10-03"},"summary":"A protein released when heart muscle cells are damaged. Doctors use it to find out whether the heart muscle has been injured, most often when someone has chest pain.","url":"https://bloodtesttracker.com/markers/troponin-i","notice":"Information, not medical advice. Ranges differ between labs, so the range on your own report is the one your result is judged against."}