{"id":"sirolimus","name":"Sirolimus","shortName":"Sirolimus","aliases":["Sirolimus, Whole Blood","Sirolimus Level","Sirolimus, LC/MS/MS","Sirolimus Trough","Sirolimus, Blood","Rapamycin","Rapamune"],"abbreviations":["SRL"],"loinc":[{"code":"29247-4","primary":true},{"code":"115766-8","primary":false},{"code":"96462-7","primary":false}],"specimen":"whole-blood","units":[{"ucum":"ng/mL","display":"ng/mL"},{"ucum":"nmol/L","display":"nmol/L"}],"referenceRanges":[{"population":"Adults","low":3,"high":18,"unit":"ng/mL","unitDisplay":"ng/mL","note":"Quest's published interval for sirolimus by LC/MS/MS in a trough sample (Quest asks for collection 1 hour before the next dose; FDA labeling describes the trough as the 24-hour concentration after a once-daily dose). It is a general guide, not a personal target. FDA labeling lists 5–15 ng/mL for lymphangioleiomyomatosis, and 16–24 ng/mL in the first year (then 12–20 ng/mL) after cyclosporine is withdrawn in kidney transplant, all as chromatographic values. Immunoassay results are not interchangeable with these.","sources":[{"title":"Sirolimus, LC/MS/MS (test code 36712)","url":"https://testdirectory.questdiagnostics.com/test/test-detail/36712/sirolimus-lcms-ms?cc=MASTER","publisher":"Quest Diagnostics"},{"title":"Sirolimus prescribing information (FDA-approved labeling, generic of Rapamune)","url":"https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=384cb547-55a4-47fc-a0a6-054c18a51b84","publisher":"DailyMed, National Library of Medicine"}]}],"review":{"status":"ai-verified","label":"AI-verified against cited sources. Awaiting expert review","lastReviewed":"2026-10-03"},"summary":"The amount of the immune-calming medicine sirolimus (rapamycin) in your blood, measured just before your next dose.","url":"https://bloodtesttracker.com/markers/sirolimus","notice":"Information, not medical advice. Ranges differ between labs, so the range on your own report is the one your result is judged against."}