{"id":"shbg","name":"Sex Hormone-Binding Globulin (SHBG)","shortName":"SHBG","aliases":["Sex Horm Binding Glob","Sex Hormone Binding Globulin","Sex Hormone-Binding Globulin","SHBG","SHBG, Serum","SHBG Serum","Sex Hormone Binding Globulin (SHBG)","Testosterone Binding Globulin","Testosterone-binding Globulin","Testosterone-Estradiol Binding Globulin","Sex Hormone Binding Protein","Sex Hormone Binding Glob","Globulina fijadora de hormonas sexuales","Sexualhormon-bindendes Globulin"],"abbreviations":["SHBG","TeBG"],"loinc":[{"code":"13967-5","primary":true},{"code":"2942-1","primary":false}],"specimen":"serum","units":[{"ucum":"nmol/L","display":"nmol/L"}],"referenceRanges":[{"population":"Men, 20–49","low":16.5,"high":55.9,"unit":"nmol/L","unitDisplay":"nmol/L","note":"Labcorp interval (Roche cobas electrochemiluminescence immunoassay), men 20-49. ARUP lists 17-56 for men 18-49 and 19-76 for men 50 and older. SHBG assays are not harmonized, so other labs can differ.","sources":[{"title":"Sex Hormone-binding Globulin (test 082016)","url":"https://www.labcorp.com/tests/082016/sex-hormone-binding-globulin","publisher":"Labcorp"},{"title":"Testosterone, Free and Total, Includes Sex Hormone-Binding Globulin (Adult Males or Individuals on Testosterone Hormone Therapy) (test 0070109)","url":"https://ltd.aruplab.com/Tests/Pub/0070109","publisher":"ARUP Laboratories"}]},{"population":"Men, 50+","low":19.3,"high":76.4,"unit":"nmol/L","unitDisplay":"nmol/L","note":"Labcorp interval for men over 49. ARUP lists 19-76 for men 50 and older.","sources":[{"title":"Sex Hormone-binding Globulin (test 082016)","url":"https://www.labcorp.com/tests/082016/sex-hormone-binding-globulin","publisher":"Labcorp"},{"title":"Testosterone, Free and Total, Includes Sex Hormone-Binding Globulin (Adult Males or Individuals on Testosterone Hormone Therapy) (test 0070109)","url":"https://ltd.aruplab.com/Tests/Pub/0070109","publisher":"ARUP Laboratories"}]},{"population":"Men, 18–19","low":17,"high":56,"unit":"nmol/L","unitDisplay":"nmol/L","note":"ARUP interval for ages 18-49. Labcorp's adult intervals start at age 20.","sources":[{"title":"Testosterone, Free and Total, Includes Sex Hormone-Binding Globulin (Adult Males or Individuals on Testosterone Hormone Therapy) (test 0070109)","url":"https://ltd.aruplab.com/Tests/Pub/0070109","publisher":"ARUP Laboratories"}]},{"population":"Women, 20–49","low":24.6,"high":122,"unit":"nmol/L","unitDisplay":"nmol/L","note":"Labcorp interval for women 20-49 (Roche cobas immunoassay). ARUP lists 25-122 for women 18-49. Pregnancy and estrogen-containing birth control raise SHBG well above this range, and no pregnancy- or contraceptive-specific interval was found in the sources opened.","sources":[{"title":"Sex Hormone-binding Globulin (test 082016)","url":"https://www.labcorp.com/tests/082016/sex-hormone-binding-globulin","publisher":"Labcorp"},{"title":"Testosterone, Free and Total, Includes Sex Hormone-Binding Globulin (Adult Males or Individuals on Testosterone Hormone Therapy) (test 0070109)","url":"https://ltd.aruplab.com/Tests/Pub/0070109","publisher":"ARUP Laboratories"}]},{"population":"Women, 50+","low":17.3,"high":125,"unit":"nmol/L","unitDisplay":"nmol/L","note":"Labcorp interval for women over 49. ARUP lists 17-125 for women 50 and older.","sources":[{"title":"Sex Hormone-binding Globulin (test 082016)","url":"https://www.labcorp.com/tests/082016/sex-hormone-binding-globulin","publisher":"Labcorp"},{"title":"Testosterone, Free and Total, Includes Sex Hormone-Binding Globulin (Adult Males or Individuals on Testosterone Hormone Therapy) (test 0070109)","url":"https://ltd.aruplab.com/Tests/Pub/0070109","publisher":"ARUP Laboratories"}]},{"population":"Women, 18–19","low":25,"high":122,"unit":"nmol/L","unitDisplay":"nmol/L","note":"ARUP interval for ages 18-49. Labcorp's adult intervals start at age 20.","sources":[{"title":"Testosterone, Free and Total, Includes Sex Hormone-Binding Globulin (Adult Males or Individuals on Testosterone Hormone Therapy) (test 0070109)","url":"https://ltd.aruplab.com/Tests/Pub/0070109","publisher":"ARUP Laboratories"}]}],"review":{"status":"ai-verified","label":"AI-verified against cited sources. Awaiting expert review","lastReviewed":"2026-10-03"},"summary":"A protein made by your liver that carries testosterone and estradiol in your blood. It helps set how much of each hormone is free to act.","url":"https://bloodtesttracker.com/markers/shbg","notice":"Information, not medical advice. Ranges differ between labs, so the range on your own report is the one your result is judged against."}