{"id":"renin-direct","name":"Renin, Direct Concentration","shortName":"Direct renin","aliases":["Renin, Direct","Direct Renin","DRC","Direct Renin Concentration","Renin Mass","Active Renin","Renin Concentration","Renina directa","Renin Direct","Direct Renin, Plasma","Renin, Direct Concentration, Plasma","Plasma Renin Concentration","Renin, Direct Immunoassay"],"abbreviations":["DRC","PRC"],"loinc":[{"code":"35570-1","primary":true},{"code":"2917-3","primary":false},{"code":"47883-4","primary":false}],"specimen":"plasma","units":[{"ucum":"pg/mL","display":"pg/mL"},{"ucum":"ng/L","display":"ng/L"}],"referenceRanges":[{"population":"18–40","low":4.2,"high":52.2,"unit":"pg/mL","unitDisplay":"pg/mL","note":"ARUP interval for blood drawn seated in the morning (LIAISON Direct Renin chemiluminescent immunoassay). For blood drawn after lying down at least 30 minutes, ARUP prints 3.2–33.2 pg/mL up to age 40 and 2.5–45.1 pg/mL over 40 (the FDA summary of the assay lists 3.1 rather than 2.5 for the over-40 lower limit). ARUP's table has no separate interval for children, and the FDA study covered healthy adults aged 18 to 65, so the rows here start at 18. Intervals are assay-specific, and many labs report in mIU/L instead: Saint Boniface Hospital (Canada, DiaSorin) prints 4.4–46 mIU/L upright and 2.8–40 mIU/L lying down for adults, and Royal Liverpool and Broadgreen NHS Trust prints 5.3–99 mIU/L upright and 4.2–60 mIU/L lying down. Results in mIU/L cannot be converted to pg/mL without the assay's own factor, so use the range printed on your own report.","sources":[{"title":"Renin, Direct (test 2001575)","url":"https://ltd.aruplab.com/Tests/Pub/2001575","publisher":"ARUP Laboratories"},{"title":"LIAISON Direct Renin 510(k) summary (K121944)","url":"https://fda.innolitics.com/device/K121944","publisher":"U.S. FDA, summary text hosted by Innolitics"},{"title":"Renin, Direct (laboratory manual)","url":"https://apps.sbgh.mb.ca/labmanual/test/view?seedId=209","publisher":"St. Boniface Hospital, Winnipeg"},{"title":"Renin, plasma (pathology test information)","url":"https://pathlabs.rlbuht.nhs.uk/renin_plasma_c.htm","publisher":"Royal Liverpool and Broadgreen University Hospitals NHS Trust"}]},{"population":"41+","low":3.6,"high":81.6,"unit":"pg/mL","unitDisplay":"pg/mL","sources":[{"title":"Renin, Direct (test 2001575)","url":"https://ltd.aruplab.com/Tests/Pub/2001575","publisher":"ARUP Laboratories"},{"title":"LIAISON Direct Renin 510(k) summary (K121944)","url":"https://fda.innolitics.com/device/K121944","publisher":"U.S. FDA, summary text hosted by Innolitics"}]}],"review":{"status":"ai-verified","label":"AI-verified against cited sources. Awaiting expert review","lastReviewed":"2026-10-03"},"summary":"Counts the amount of active renin, a kidney enzyme that helps control blood pressure and salt balance. It is not the same test as renin activity.","url":"https://bloodtesttracker.com/markers/renin-direct","notice":"Information, not medical advice. Ranges differ between labs, so the range on your own report is the one your result is judged against."}