{"id":"non-hdl-cholesterol","name":"Non-HDL Cholesterol","shortName":"Non-HDL-C","aliases":["Non-HDL-C","Non HDL Chol","Cholesterol, Non-HDL","Non-HDL Chol (calc)","Colesterol no HDL","Non-HDL-Cholesterin","Non-HDL Cholesterol","Non-HDL Cholesterol (calculated)","Cholesterol, Non-HDL, Calculated, S","Cholesterol Non-HDL","Non-HDL Cholesterol, Calculated","Non-HDL","Nonhdl Cholesterol","Cholesterol non HDL","Colesterol no-HDL","Non-HDL-C (calc)"],"abbreviations":["Non-HDL-C","non-HDL","NHDL-C"],"loinc":[{"code":"43396-1","primary":true},{"code":"70204-3","primary":false}],"specimen":"calculated","units":[{"ucum":"mg/dL","display":"mg/dL"},{"ucum":"mmol/L","display":"mmol/L"},{"ucum":"g/L","display":"g/L"}],"referenceRanges":[{"population":"20+","low":null,"high":129,"unit":"mg/dL","unitDisplay":"mg/dL","note":"The 'desirable' level: below 130 mg/dL (3.4 mmol/L). Mayo and Quest print it for adults, MedlinePlus calls it healthy and Mayo Clinic calls it optimal for most people, and it sits 30 mg/dL above the 'optimal' LDL cutoff of 100 (ATP III, ARUP). It is also the 2026 ACC/AHA goal for adults at borderline or intermediate heart risk. Goals are lower with higher risk: below 100 mg/dL (2.6 mmol/L) at high risk, and below 85 mg/dL (2.2 mmol/L) at very high risk with established heart or artery disease (2026 ACC/AHA; ESC/EAS 2019 uses the same three numbers for moderate, high and very high risk). NHS England guidance uses 2.6 mmol/L in secondary prevention. A European consensus suggested flagging non-HDL at 150 mg/dL (3.9 mmol/L) on non-fasting samples. Mayo applies the adult range from age 18; Quest from age 20.","sources":[{"title":"Lipid Panel, Serum (test ID LPSC1)","url":"https://www.testcatalog.org/show/LPSC1","publisher":"Mayo Clinic Laboratories (Extended Catalog copy)","year":2026},{"title":"Lipid Panel with Ratios, Quest Diagnostics (reference ranges as listed by Fullscript)","url":"https://us.fullscript.com/labs/quest/lipid-panel-with-ratios","publisher":"Quest Diagnostics (via Fullscript)"},{"title":"Cholesterol Levels: MedlinePlus Medical Test","url":"https://medlineplus.gov/lab-tests/cholesterol-levels/","publisher":"MedlinePlus (National Library of Medicine)"},{"title":"Cholesterol ratio or non-HDL cholesterol: Which is most important? (read from a 2025 Internet Archive copy)","url":"https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/expert-answers/cholesterol-ratio/faq-20058006","publisher":"Mayo Clinic"},{"title":"Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III): Executive Summary","url":"https://www.nhlbi.nih.gov/files/docs/guidelines/atp3xsum.pdf","publisher":"NHLBI / National Institutes of Health","year":2001},{"title":"Lipid Panel (test 0020421)","url":"https://ltd.aruplab.com/Tests/Pub/0020421","publisher":"ARUP Laboratories"},{"title":"Lipid Profile Testing and Interpretation (summarizes the 2026 ACC/AHA Dyslipidemia Guideline)","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13339843/","publisher":"Circulation (Nguyen, Ahmad, Navar)","year":2026},{"title":"The 2026 ACC/AHA Dyslipidemia Guideline: A Critical and Transatlantic Perspective on Personalized Lipid Management","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13608459/","publisher":"Life (MDPI)","year":2026},{"title":"Understanding the new dyslipidemia guidelines","url":"https://www.questdiagnostics.com/healthcare-professionals/provider-insights/articles/understanding-the-new-dyslipidemia-guidelines","publisher":"Quest Diagnostics","year":2026},{"title":"2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk","url":"https://academic.oup.com/eurheartj/article/41/1/111/5556353","publisher":"European Society of Cardiology / European Atherosclerosis Society","year":2019},{"title":"Importance and Management of Non-High-Density Lipoprotein Cholesterol in Dyslipidemia Treatment","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13080752/","publisher":"JACC: Asia","year":2026},{"title":"Fasting is not routinely required for determination of a lipid profile: clinical and laboratory implications including flagging at desirable concentration cutpoints. A joint consensus statement from the European Atherosclerosis Society and European Federation of Clinical Chemistry and Laboratory Medicine","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4929379/","publisher":"European Heart Journal (joint EAS/EFLM statement, also in Clinical Chemistry)","year":2016},{"title":"Summary of National Guidance for Lipid Management for Primary and Secondary Prevention of CVD (version 7)","url":"https://www.england.nhs.uk/aac/wp-content/uploads/sites/50/2020/04/lipid-management-pathway-version-7-March-2024.pdf","publisher":"NHS England Accelerated Access Collaborative","year":2024}]}],"review":{"status":"ai-verified","label":"AI-verified against cited sources. Awaiting expert review","lastReviewed":"2026-10-03"},"summary":"All the cholesterol in your blood except HDL. It is total cholesterol minus HDL, and it counts every particle that can build up in artery walls.","url":"https://bloodtesttracker.com/markers/non-hdl-cholesterol","notice":"Information, not medical advice. Ranges differ between labs, so the range on your own report is the one your result is judged against."}