{"id":"mpo-anca","name":"MPO-ANCA (Anti-Myeloperoxidase Antibody)","shortName":"MPO-ANCA","aliases":["MPO Antibody","MPO ANCA","Myeloperoxidase Antibody","Anti-MPO","MPO Ab (ANCA)","Myeloperoxidase IgG","Myeloperoxidase Antibody (MPO)","Myeloperoxidase Antibodies, IgG, Serum","Myeloperoxidase Antibodies","Myeloperoxidase Ab, S","Myeloperoxidase (MPO) Ab, IgG","Myeloperoxidase (MPO) Antibody","Antimyeloperoxidase (MPO) Antibodies","Anti-MPO Antibodies","Anti-MPO Antibody","Anti-MPO IgG","Anti-Myeloperoxidase Antibody","MPO-ANCA IgG","Myeloperoxidase ANCA"],"abbreviations":["MPO-ANCA","MPO Ab","Anti-MPO","MPO ANCA"],"loinc":[{"code":"46266-3","primary":true},{"code":"6969-0","primary":false},{"code":"48404-8","primary":false},{"code":"97996-3","primary":false},{"code":"29643-4","primary":false},{"code":"17316-1","primary":false}],"specimen":"serum","units":[{"ucum":"[arb'U]/mL","display":"AU/mL"}],"referenceRanges":[{"population":"Adults","low":0,"high":19,"unit":"[arb'U]/mL","unitDisplay":"AU/mL","note":"ARUP's multiplex bead assay, reported in AU/mL: 19 or less is negative, 20 to 25 is equivocal and 26 or more is positive. Other labs use different scales, and the numbers cannot be compared. Quest's immunoassay reports an antibody index (AI): below 1.0 AI is 'no antibody detected' and 1.0 AI or more is 'antibody detected'. Mayo Clinic Laboratories reports units (U): below 0.4 is negative, 0.4 to 0.9 equivocal and 1.0 or more positive. Labcorp's fluoroenzyme immunoassay (EliA) reports U/mL: below 3.5 is negative, 3.5 to 5.0 equivocal and above 5.0 positive. This range applies only to results printed in AU/mL, so use the cutoff and flag on your own report.","sources":[{"title":"Myeloperoxidase (MPO) Antibody (test 0050526)","url":"https://ltd.aruplab.com/Tests/Pub/0050526","publisher":"ARUP Laboratories"},{"title":"MPO/PR3 (ANCA) Antibodies (test 0050707)","url":"https://ltd.aruplab.com/Tests/Pub/0050707","publisher":"ARUP Laboratories"}]}],"review":{"status":"ai-verified","label":"AI-verified against cited sources. Awaiting expert review","lastReviewed":"2026-10-03"},"summary":"A blood test for antibodies against myeloperoxidase, a protein in white blood cells. A positive result is linked to some types of blood vessel inflammation (vasculitis).","url":"https://bloodtesttracker.com/markers/mpo-anca","notice":"Information, not medical advice. Ranges differ between labs, so the range on your own report is the one your result is judged against."}