{"id":"insulin-autoantibodies","name":"Insulin Autoantibodies (IAA)","shortName":"IAA","aliases":["Insulin Antibody","Insulin Autoantibodies","IAA","Anti-Insulin Antibody","Insulin Ab","Insulin Antibodies","Insulin Antibodies, Serum","Anti-Insulin Antibodies","Insulin Autoantibody","Human Insulin Antibodies","Insulin Antibody (IAA)","Anti-Insulin Autoantibodies","Insulin AB"],"abbreviations":["IAA"],"loinc":[{"code":"8072-1","primary":true},{"code":"56546-5","primary":false},{"code":"5232-4","primary":false},{"code":"2481-0","primary":false}],"specimen":"serum","units":[{"ucum":"[arb'U]/mL","display":"U/mL"}],"referenceRanges":[{"population":"Adults","low":0,"high":0.4,"unit":"[arb'U]/mL","unitDisplay":"U/mL","note":"ARUP's radioimmunoassay reports in Kronus units, which ARUP says are arbitrary and equal U/mL, with a reference of 0.0 to 0.4 and anything above 0.4 positive. A published case series used the same RSR radioimmunoassay with a normal range below 0.4 U/mL. Other assays use other scales: the lab shown in Mayo's catalog (Esoterix) reports micro-units per mL and calls less than 5.0 uU/mL negative, and one ELISA kit uses a cutoff of 10 U/mL. These scales are not interchangeable, so use the cutoff and flag printed on your own report.","sources":[{"title":"Insulin Antibody (ARUP test 0099228)","url":"https://ltd.aruplab.com/Tests/Pub/0099228","publisher":"ARUP Laboratories","year":2026},{"title":"Assessment and Management of Anti-Insulin Autoantibodies in Varying Presentations of Insulin Autoimmune Syndrome","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6179165/","publisher":"Journal of Clinical Endocrinology & Metabolism 2018;103:3845-3855","year":2018}]}],"review":{"status":"ai-verified","label":"AI-verified against cited sources. Awaiting expert review","lastReviewed":"2026-10-03"},"summary":"Measures antibodies to insulin, used to look for autoimmune (type 1) diabetes before insulin treatment or to find antibodies to injected insulin.","url":"https://bloodtesttracker.com/markers/insulin-autoantibodies","notice":"Information, not medical advice. Ranges differ between labs, so the range on your own report is the one your result is judged against."}