{"id":"igfbp-3","name":"IGFBP-3 (IGF Binding Protein 3)","shortName":"IGFBP-3","aliases":["IGF Binding Protein-3","IGFBP-3","Insulin-like Growth Factor Binding Protein 3","IGFBP3","IGFBP-3, Serum","IGF-BP3","IGF Binding Protein 3","Insulin-like Growth Factor-binding Protein 3 (IGFBP-3)","Insulin-Like Growth Factor-Binding Protein 3, Serum","Somatomedin C Binding Protein","IGFBP-3, S"],"abbreviations":["IGFBP-3","IGFBP3","IGF-BP3"],"loinc":[{"code":"2483-6","primary":true},{"code":"33808-7","primary":false}],"specimen":"serum","units":[{"ucum":"mg/L","display":"mg/L"},{"ucum":"ug/mL","display":"µg/mL"},{"ucum":"ug/L","display":"µg/L"}],"referenceRanges":[{"population":"Men, 18","low":2678,"high":6327,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Women, 18","low":2749,"high":6510,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Men, 19","low":2700,"high":6341,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Women, 19","low":2779,"high":6527,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Men, 20","low":2723,"high":6361,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Women, 20","low":2809,"high":6550,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Men, 21–25","low":2753,"high":6361,"unit":"ug/L","unitDisplay":"µg/L","note":"Labcorp interval (IDS-iSYS immunochemiluminometric assay, based on Friedrich 2014). Other labs differ. Mayo prints 3.4 to 7.8 mcg/mL (the same as mg/L) for this age, with no split by sex (Immulite 2000 assay). Eurofins Biomnis in France lists 2.27 to 4.23 mg/L for ages 18 to 40, taken from a 1993 study. Quest prints age-specific ranges only on the report. Labs report in mg/L, µg/mL (the same number as mg/L) or µg/L (1,000 times larger), so check the unit. IGFBP-3 assays vary a lot between platforms, so use the range on your own report.","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"},{"title":"IGFB3: Insulin-Like Growth Factor-Binding Protein 3, Serum","url":"https://www.mayocliniclabs.com/test-catalog/overview/83300","publisher":"Mayo Clinic Laboratories"},{"title":"IGF Binding Protein-3 (IGFBP-3) (test code 34458)","url":"https://testdirectory.questdiagnostics.com/test/test-detail/34458/?cc=MASTER","publisher":"Quest Diagnostics"},{"title":"IGFBP-3 (preanalytical recommendations and reference values)","url":"https://www.eurofins-biomnis.com/referentiel/liendoc/precis/IGFBP3.pdf","publisher":"Eurofins Biomnis"},{"title":"Insulin-like growth factor binding protein 3 (IGFBP-3) conversion calculator","url":"https://unitslab.com/node/168","publisher":"UnitsLab"}]},{"population":"Women, 21–25","low":2855,"high":6559,"unit":"ug/L","unitDisplay":"µg/L","note":"Labcorp interval (IDS-iSYS immunochemiluminometric assay, based on Friedrich 2014). Other labs differ. Mayo prints 3.4 to 7.8 mcg/mL (the same as mg/L) for this age, with no split by sex (Immulite 2000 assay). Eurofins Biomnis in France lists 2.27 to 4.23 mg/L for ages 18 to 40, taken from a 1993 study. Quest prints age-specific ranges only on the report. Labs report in mg/L, µg/mL (the same number as mg/L) or µg/L (1,000 times larger), so check the unit. IGFBP-3 assays vary a lot between platforms, so use the range on your own report.","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"},{"title":"IGFB3: Insulin-Like Growth Factor-Binding Protein 3, Serum","url":"https://www.mayocliniclabs.com/test-catalog/overview/83300","publisher":"Mayo Clinic Laboratories"},{"title":"IGF Binding Protein-3 (IGFBP-3) (test code 34458)","url":"https://testdirectory.questdiagnostics.com/test/test-detail/34458/?cc=MASTER","publisher":"Quest Diagnostics"},{"title":"IGFBP-3 (preanalytical recommendations and reference values)","url":"https://www.eurofins-biomnis.com/referentiel/liendoc/precis/IGFBP3.pdf","publisher":"Eurofins Biomnis"},{"title":"Insulin-like growth factor binding protein 3 (IGFBP-3) conversion calculator","url":"https://unitslab.com/node/168","publisher":"UnitsLab"}]},{"population":"Men, 26–30","low":2683,"high":6127,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Women, 26–30","low":2752,"high":6219,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Men, 31–35","low":2610,"high":5977,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Women, 31–35","low":2573,"high":5804,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Men, 36–40","low":2571,"high":5982,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Women, 36–40","low":2504,"high":5709,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Men, 41–45","low":2515,"high":6018,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Women, 41–45","low":2409,"high":5610,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Men, 46–50","low":2374,"high":5891,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Women, 46–50","low":2343,"high":5612,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Men, 51–55","low":2251,"high":5808,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Women, 51–55","low":2306,"high":5703,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Men, 56–60","low":2133,"high":5711,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Women, 56–60","low":2238,"high":5717,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Men, 61–65","low":2027,"high":5610,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Women, 61–65","low":2161,"high":5691,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Men, 66–70","low":1926,"high":5487,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Women, 66–70","low":2059,"high":5572,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Men, 71–75","low":1779,"high":5201,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Women, 71–75","low":2005,"high":5549,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Men, 76–80","low":1673,"high":5015,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Women, 76–80","low":1950,"high":5490,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Men, 81–85","low":1632,"high":5014,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Women, 81–85","low":1925,"high":5498,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Men, 86–90","low":1665,"high":5239,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]},{"population":"Women, 86–90","low":1961,"high":5672,"unit":"ug/L","unitDisplay":"µg/L","sources":[{"title":"Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) (test 140152)","url":"https://www.labcorp.com/tests/140152/insulin-like-growth-factor-binding-protein-3-igfbp-3","publisher":"Labcorp"}]}],"review":{"status":"ai-verified","label":"AI-verified against cited sources. Awaiting expert review","lastReviewed":"2026-10-03"},"summary":"A protein made mostly in the liver that carries IGF-1 in the blood. It rises and falls with growth hormone and with nutrition, and usual levels change a lot with age.","url":"https://bloodtesttracker.com/markers/igfbp-3","notice":"Information, not medical advice. Ranges differ between labs, so the range on your own report is the one your result is judged against."}