{"id":"ige-dog-dander","name":"Dog Dander IgE","shortName":"Dog dander IgE","aliases":["E005-IgE Dog Dander","e5","Dog dander (e5) IgE","e5 IgE","Dog Dander IgE","Dog dander e5","Canis familiaris dander IgE","Allergen, Animal, Dog Dander IgE","Allergen, Epidermals and Animal Proteins, Dog Dander"],"abbreviations":["e5","E005"],"loinc":[{"code":"6098-8","primary":true}],"specimen":"serum","units":[{"ucum":"kU/L","display":"kU/L"},{"ucum":"U/mL","display":"UA/mL"}],"referenceRanges":[{"population":"Adults","low":0,"high":0.1,"unit":"kU/L","unitDisplay":"kU/L","note":"Quest, Labcorp and ARUP all print a result under 0.10 kU/L as class 0 (absent, negative or no significant level), and 0.10 is also the lowest value the ImmunoCAP assay reports. Thermo Fisher, which makes the assay, treats results of 0.1 kUA/L or more as detected sensitization. Labs disagree about the 0.10 to 0.34 zone: Quest calls it a very low level, ARUP calls its clinical relevance undetermined (and lists 0.34 kU/L or less as its reference interval for this test), and Labcorp flags results from 0.10 kU/L upward, calling 0.10 to 0.31 class 0/I (equivocal or low). The older cutoff of 0.35 kU/L is still used in many studies, including the US NHANES survey, and a few labs go further: Children's Minnesota reports anything under 0.35 kU/L as negative. Labcorp's own follow-up rule for dog uses a similar cutoff: its report says dog IgE above 0.34 kU/L triggered extra component tests. Labs print results below the limit as '<0.10', and a printed 0.10 is already class 0/1. A result above the range shows sensitization, not that you have an allergy (NIAID 2010, WAO 2020), and results from different labs or assay systems may not be comparable. Dog extract results blend several dog proteins, and one of them (Can f 5) is made only by male dogs (Kozlov 2025); no dog breed has been shown to be hypoallergenic (Vredegoor 2012).","sources":[{"title":"ImmunoCAP Epidermal and Animal Protein Allergens (Thermo Fisher product page; lists e5 dog dander; measuring range 0.1 to 100 kUA/L)","url":"https://www.thermofisher.com/order/catalog/product/14501510","publisher":"Thermo Fisher Scientific"},{"title":"Allergen, Epidermals and Animal Proteins, Dog Dander (test 0099568)","url":"https://ltd.aruplab.com/Tests/Pub/0099568","publisher":"ARUP Laboratories"},{"title":"Allergens, Inhalants, Comprehensive Profile IgE (test 0055312)","url":"https://ltd.aruplab.com/Tests/Pub/0055312","publisher":"ARUP Laboratories"},{"title":"Allergen Profile With Component Reflexes, Respiratory, Area 2 (test 607111)","url":"https://www.labcorp.com/tests/607111/allergen-profile-with-component-reflexes-respiratory-area-2","publisher":"Labcorp"},{"title":"Sample patient report: Allergens with Component Reflex, Area 20 (test 607120)","url":"https://files.labcorp.com/testmenu-d8/sample_reports/607120.pdf","publisher":"Labcorp","year":2021},{"title":"ImmunoCAP Specific IgE Blood Test: Allergy Test List (interpretation table and test codes)","url":"https://www.questdiagnostics.com/content/dam/corporate/restricted/documents/hcp/about-our-tests/TL3930_Allergy%20Test%20list%202017.pdf","publisher":"Quest Diagnostics","year":2017},{"title":"ImmunoCAP Specific IgE blood test results: Interpretation (respiratory results interpretation guide)","url":"https://corporate.thermofisher.com/content/dam/phadia/library/en/Respiratory%20Results%20Interpretation%20Guide.pdf","publisher":"Thermo Fisher Scientific (Phadia)","year":2023},{"title":"Prevalence of allergic sensitization in the United States: results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4119838/","publisher":"Journal of Allergy and Clinical Immunology","year":2014},{"title":"Guidelines for the Diagnosis and Management of Food Allergy in the United States: Report of the NIAID-Sponsored Expert Panel","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4241964/","publisher":"NIAID / Journal of Allergy and Clinical Immunology","year":2010},{"title":"IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7044795/","publisher":"World Allergy Organization Journal","year":2020},{"title":"Recombinant IgE-Reactive Functional Can f 5 Devoid of Cross-Reactive Carbohydrate Determinants","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12186582/","publisher":"Allergy","year":2025},{"title":"Can f 1 levels in hair and homes of different dog breeds: lack of evidence to describe any dog breed as hypoallergenic","url":"https://pubmed.ncbi.nlm.nih.gov/22728082/","publisher":"Journal of Allergy and Clinical Immunology","year":2012},{"title":"Allergen IgE (laboratory test manual entry; class table and reporting rules)","url":"https://www.childrensmn.org/Manuals/Lab/chemistry/allergen-ige.pdf","publisher":"Children's Minnesota","year":2018},{"title":"ImmunoCAP Specific IgE: Dog allergy (testing algorithm)","url":"https://corporate.thermofisher.com/content/dam/phadia/library/en/immunocap-testing-algorithms/Immunocap-testing-algorithm-Dog-EN.pdf","publisher":"Thermo Fisher Scientific (Phadia)","year":2025}]}],"review":{"status":"ai-verified","label":"AI-verified against cited sources. Awaiting expert review","lastReviewed":"2026-10-03"},"summary":"Shows whether your immune system has made IgE antibodies to proteins from dog skin flakes, hair and saliva.","url":"https://bloodtesttracker.com/markers/ige-dog-dander","notice":"Information, not medical advice. Ranges differ between labs, so the range on your own report is the one your result is judged against."}