{"id":"ige-cladosporium","name":"Cladosporium herbarum IgE","shortName":"Cladosporium IgE","aliases":["Cladosporium herbarum IgE","Cladosporium IgE","M002-IgE Cladosporium herbarum","Cladosporium herbarum (m2) IgE","Cladosporium herbarum (m2)","m2 IgE","Allergen, Fungi/Mold, Hormodendrum IgE","Hormodendrum IgE","Hormodendrum (Cladosporium) IgE","Mold, Cladosporium herbarum IgE"],"abbreviations":["m2","M002"],"loinc":[{"code":"6075-6","primary":true},{"code":"112138-3","primary":false}],"specimen":"serum","units":[{"ucum":"kU/L","display":"kU/L"},{"ucum":"U/mL","display":"UA/mL"}],"referenceRanges":[{"population":"Adults","low":0,"high":0.1,"unit":"kU/L","unitDisplay":"kU/L","note":"Quest, Labcorp and ARUP all print a result under 0.10 kU/L as class 0 (absent, negative or no significant level), and 0.10 is also the lowest value the ImmunoCAP assay reports. Thermo Fisher, which makes the assay, treats results of 0.1 kUA/L or more as detected sensitization. Labs disagree about the 0.10 to 0.34 zone: Quest calls it a very low level, ARUP calls its clinical relevance undetermined (and lists 0.34 kU/L or less as its reference interval for this test), and Labcorp flags results from 0.10 kU/L upward, calling 0.10 to 0.31 class 0/I (equivocal or low). The older cutoff of 0.35 kU/L is still used in many studies, including the US NHANES survey, and a few labs go further: Children's Minnesota reports anything under 0.35 kU/L as negative. Labs print results below the limit as '<0.10', and a printed 0.10 is already class 0/1. A result above the range shows sensitization, not that you have an allergy (NIAID 2010, WAO 2020), and results from different labs or assay systems may not be comparable. Mold extracts vary more from batch to batch than most allergen extracts, which adds to the spread between labs (Pfeiffer 2023). Mold spore counts follow temperature, rain and humidity (Anees-Hill 2022), and fungal sensitization is linked to more severe asthma (Denning 2014).","sources":[{"title":"ImmunoCAP Mold and Yeast Allergens (Thermo Fisher product page; lists m2 Cladosporium herbarum; measuring range 0.1 to 100 kUA/L)","url":"https://www.thermofisher.com/order/catalog/product/14520210","publisher":"Thermo Fisher Scientific"},{"title":"M002-IgE Cladosporium herbarum (test 602462)","url":"https://www.labcorp.com/tests/602462/cladosporium-herbarum","publisher":"Labcorp"},{"title":"Allergens, Inhalants, Comprehensive Profile IgE (test 0055312)","url":"https://ltd.aruplab.com/Tests/Pub/0055312","publisher":"ARUP Laboratories"},{"title":"Allergens, Mold Profile, Southeast Comprehensive (test 0055387)","url":"https://ltd.aruplab.com/Tests/Pub/0055387","publisher":"ARUP Laboratories"},{"title":"Sample patient report: Allergens with Component Reflex, Area 20 (test 607120)","url":"https://files.labcorp.com/testmenu-d8/sample_reports/607120.pdf","publisher":"Labcorp","year":2021},{"title":"ImmunoCAP Specific IgE Blood Test: Allergy Test List (interpretation table and test codes)","url":"https://www.questdiagnostics.com/content/dam/corporate/restricted/documents/hcp/about-our-tests/TL3930_Allergy%20Test%20list%202017.pdf","publisher":"Quest Diagnostics","year":2017},{"title":"ImmunoCAP Specific IgE blood test results: Interpretation (respiratory results interpretation guide)","url":"https://corporate.thermofisher.com/content/dam/phadia/library/en/Respiratory%20Results%20Interpretation%20Guide.pdf","publisher":"Thermo Fisher Scientific (Phadia)","year":2023},{"title":"Prevalence of allergic sensitization in the United States: results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4119838/","publisher":"Journal of Allergy and Clinical Immunology","year":2014},{"title":"Guidelines for the Diagnosis and Management of Food Allergy in the United States: Report of the NIAID-Sponsored Expert Panel","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4241964/","publisher":"NIAID / Journal of Allergy and Clinical Immunology","year":2010},{"title":"IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7044795/","publisher":"World Allergy Organization Journal","year":2020},{"title":"Problems Encountered Using Fungal Extracts as Test Solutions for Fungal Allergy Diagnosis","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10607634/","publisher":"Journal of Fungi","year":2023},{"title":"Fungal allergy in asthma: state of the art and research needs","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4005466/","publisher":"Clinical and Translational Allergy","year":2014},{"title":"A systematic review of outdoor airborne fungal spore seasonality across Europe and the implications for health","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8919338/","publisher":"Science of the Total Environment","year":2022},{"title":"Allergen IgE (laboratory test manual entry; class table and reporting rules)","url":"https://www.childrensmn.org/Manuals/Lab/chemistry/allergen-ige.pdf","publisher":"Children's Minnesota","year":2018}]}],"review":{"status":"ai-verified","label":"AI-verified against cited sources. Awaiting expert review","lastReviewed":"2026-10-03"},"summary":"Shows whether your immune system has made IgE antibodies to Cladosporium herbarum, a common indoor and outdoor mold.","url":"https://bloodtesttracker.com/markers/ige-cladosporium","notice":"Information, not medical advice. Ranges differ between labs, so the range on your own report is the one your result is judged against."}