{"id":"ige-alpha-gal","name":"Alpha-gal IgE","shortName":"Alpha-gal IgE","aliases":["Galactose-alpha-1,3-galactose IgE","O215-IgE Alpha-Gal","o215 IgE","Alpha-Gal IgE","Galactose-Alpha-1,3-Galactose (Alpha-Gal), IgE, Serum","Galactose-alpha-1,3-galactose, IgE","Allergen, Food, Alpha-Gal (galactose-alpha-1,3-galatose) IgE","Alpha Gal IgE","alpha-gal sIgE","α-Gal IgE","Galactose Alpha 1,3 Galactose IgE","Alpha-Gal (o215) IgE","ImmunoCAP o215"],"abbreviations":["o215","α-Gal"],"loinc":[{"code":"73837-7","primary":true}],"specimen":"serum","units":[{"ucum":"kU/L","display":"kU/L"}],"referenceRanges":[{"population":"Adults","low":0,"high":0.09,"unit":"kU/L","unitDisplay":"kU/L","note":"Most labs print a result under 0.10 kU/L as negative (class 0). Mayo Clinic Laboratories lists 0.10 to 0.69 kU/L as borderline or equivocal and flags 0.70 and above, and its reference values apply to all ages. ARUP calls 0.10 to 0.34 kU/L 'clinical relevance undetermined'. Published studies have used cutoffs of 0.1 and 0.35 IU/mL for a positive result. The CDC says a positive test alone does not mean a person has alpha-gal syndrome, especially where lone star ticks live, and reactions usually start 2 to 6 hours after eating, so timing and history matter as much as the number.","sources":[{"title":"Galactose-Alpha-1,3-Galactose (Alpha-Gal), IgE, Serum (test ID ALGAL)","url":"https://www.mayocliniclabs.com/test-catalog/overview/609737","publisher":"Mayo Clinic Laboratories"},{"title":"Allergen, Food, Alpha-Gal (galactose-alpha-1,3-galatose) IgE (ARUP test 3003923)","url":"https://ltd.aruplab.com/Tests/Pub/3003923","publisher":"ARUP Laboratories"},{"title":"Galactose-Alpha-1,3-Galactose (Alpha-Gal), IgE, Serum (Labcorp test 650001)","url":"https://www.labcorp.com/tests/650001","publisher":"Labcorp"},{"title":"About Alpha-gal Syndrome","url":"https://www.cdc.gov/alpha-gal-syndrome/about/","publisher":"Centers for Disease Control and Prevention","year":2026},{"title":"Clinical Diagnosis and Testing (Alpha-gal Syndrome)","url":"https://www.cdc.gov/alpha-gal-syndrome/hcp/diagnosis-testing/","publisher":"Centers for Disease Control and Prevention","year":2026},{"title":"Symptoms of Alpha-gal Syndrome","url":"https://www.cdc.gov/alpha-gal-syndrome/signs-symptoms/","publisher":"Centers for Disease Control and Prevention","year":2026},{"title":"On the cause and consequences of IgE to galactose-alpha-1,3-galactose: A report from the National Institute of Allergy and Infectious Diseases Workshop on Understanding IgE-Mediated Mammalian Meat Allergy","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7301618/","publisher":"Journal of Allergy and Clinical Immunology","year":2020},{"title":"510(k) Decision Memorandum K173726: ImmunoCAP Specific IgE (ImmunoCAP Allergen f447, rAra h 6, Peanut)","url":"https://www.accessdata.fda.gov/cdrh_docs/reviews/K173726.pdf","publisher":"U.S. Food and Drug Administration","year":2018}]}],"review":{"status":"ai-verified","label":"AI-verified against cited sources. Awaiting expert review","lastReviewed":"2026-10-03"},"summary":"Measures IgE antibodies to alpha-gal, a sugar found in red meat and other mammal products. It is linked to a tick-related allergy that causes delayed reactions.","url":"https://bloodtesttracker.com/markers/ige-alpha-gal","notice":"Information, not medical advice. Ranges differ between labs, so the range on your own report is the one your result is judged against."}