{"id":"estradiol","name":"Estradiol (E2)","shortName":"Estradiol","aliases":["Estradiol","E2","Estradiol, Sensitive","Estradiol, Ultrasensitive, LC/MS","17-beta Estradiol","Estradiol, Serum","Oestradiol","Estradiol, Sensitive (LC/MS)","17β-estradiol","Estradiol (E2)","Estradiol, Ultrasensitive","Estradiol, LC/MS/MS","Estradiol LC-MS/MS","17-Beta-Estradiol","Estradiol, 17 Beta","Estradiol, 17b","Estradiol by Immunoassay","Estradiol by Mass Spec","Estradiol, Rapid, Immunoassay","Ultrasensitive Estradiol","E2 IVF","IVF Estradiol"],"abbreviations":["E2"],"loinc":[{"code":"2243-4","primary":true},{"code":"14715-7","primary":false},{"code":"35384-7","primary":false},{"code":"72873-3","primary":false}],"specimen":"serum-or-plasma","units":[{"ucum":"pg/mL","display":"pg/mL"},{"ucum":"pmol/L","display":"pmol/L"}],"referenceRanges":[{"population":"Men, 18+","low":7.6,"high":42.6,"unit":"pg/mL","unitDisplay":"pg/mL","note":"Labcorp interval (Roche ECLIA immunoassay). Immunoassays can read too high at low levels, so a sensitive LC-MS/MS test is preferred for men. Quest and Labcorp recommend it, and ARUP offers a separate LC-MS/MS test for men: Mayo (LC-MS/MS) lists 10–40, ARUP (LC-MS/MS) lists 10–42 for ages 18 and over, and Labcorp's sensitive test lists 8–35 pg/mL. MedlinePlus notes that men's estrogen levels change little through life.","sources":[{"title":"Estradiol (test 004515)","url":"https://www.labcorp.com/tests/004515/estradiol","publisher":"Labcorp"},{"title":"EEST - Estradiol, Serum","url":"https://www.mayocliniclabs.com/test-catalog/overview/81816/estradiol-serum","publisher":"Mayo Clinic Laboratories"},{"title":"Estradiol (Adult Males, Children, Postmenopausal Females, or Individuals on Estrogen-Suppressing Hormone Therapy) (test 0093247)","url":"https://ltd.aruplab.com/Tests/Pub/0093247","publisher":"ARUP Laboratories"},{"title":"Estradiol, Sensitive, LC/MS (test 140244)","url":"https://www.labcorp.com/tests/140244/estradiol-sensitive-lc-ms","publisher":"Labcorp"},{"title":"Challenges to the Measurement of Estradiol: An Endocrine Society Position Statement","url":"https://pubmed.ncbi.nlm.nih.gov/23463657/","publisher":"Journal of Clinical Endocrinology & Metabolism","year":2013},{"title":"Estradiol (test code 4021)","url":"https://testdirectory.questdiagnostics.com/test/test-detail/4021/estradiol?cc=MASTER","publisher":"Quest Diagnostics"},{"title":"Estrogen Levels Test","url":"https://medlineplus.gov/lab-tests/estrogen-levels-test/","publisher":"MedlinePlus (NIH)"}]}],"review":{"status":"ai-verified","label":"AI-verified against cited sources. Awaiting expert review","lastReviewed":"2026-10-03"},"summary":"The main estrogen in women of childbearing age. It rises and falls through the menstrual cycle and drops after menopause.","url":"https://bloodtesttracker.com/markers/estradiol","notice":"Information, not medical advice. Ranges differ between labs, so the range on your own report is the one your result is judged against."}