{"id":"anti-dsdna","name":"Anti-dsDNA Antibody (quantitative)","shortName":"Anti-dsDNA","aliases":["Anti-dsDNA","dsDNA Antibody","Double-Stranded DNA Antibody","DNA (Double Stranded) Antibody","Anti-DNA, Double Stranded","dsDNA Ab IgG","DNA (ds) Ab","dsDNA antibodies","Anti-double stranded DNA","Double-Stranded DNA (dsDNA) Antibody, IgG","Double-Stranded DNA (dsDNA) Antibody, IgG by ELISA","dsDNA Ab, IgG, S","ds DNA Ab","ds-DNA","ds-DNA IgG","Anti-Native DNA","Native double-stranded DNA antibody","Antibody to ds-DNA","Anti-dsDNA Antibody","DNA (ds) Antibody","Anti-DNA (DS) Ab Qn"],"abbreviations":["anti-dsDNA","dsDNA","dsDNA Ab"],"loinc":[{"code":"5130-0","primary":true},{"code":"33799-8","primary":false},{"code":"32677-7","primary":false},{"code":"58465-6","primary":false}],"specimen":"serum","units":[{"ucum":"[IU]/mL","display":"IU/mL"}],"referenceRanges":[{"population":"Adults","low":0,"high":4,"unit":"[IU]/mL","unitDisplay":"IU/mL","note":"Negative cutoff of 4 IU/mL or less as printed by University of Iowa Hospitals for a multiplex immunoassay (5 to 9 indeterminate, 10 or more positive). Cutoffs are assay-specific and labs disagree widely: ARUP (ELISA) reports 24 IU/mL or less as negative, 25 to 30 as borderline positive, above 30 up to 60 as low positive, above 60 up to 200 as positive and above 200 as strong positive, and Mayo Clinic Laboratories (ELISA) reports below 100 IU/mL as negative. The lowest of these cutoffs is used here so that a result a lab calls positive is not shown as in the usual range. This is a cutoff for a positive result on one method rather than a general range, so use the cutoff and flag printed on your own report.","sources":[{"title":"Double Stranded DNA Antibody","url":"https://www.healthcare.uiowa.edu/path_handbook/rhandbook/test681.html","publisher":"UI Health Care (University of Iowa Hospitals & Clinics) Laboratory Services Handbook"},{"title":"Double-Stranded DNA (dsDNA) Antibody, IgG by ELISA with Reflex to dsDNA Antibody, IgG by IFA (test 0050215)","url":"https://ltd.aruplab.com/Tests/Pub/0050215","publisher":"ARUP Laboratories"},{"title":"Double-Stranded DNA (dsDNA) Antibodies, IgG, Serum (test ADNA1)","url":"https://www.testcatalog.org/show/ADNA1","publisher":"Mayo Clinic Laboratories (Extended Catalog)"}]}],"review":{"status":"ai-verified","label":"AI-verified against cited sources. Awaiting expert review","lastReviewed":"2026-10-03"},"summary":"Antibodies that target your own DNA. A positive result is linked to lupus, and in people with lupus the level is sometimes followed over time.","url":"https://bloodtesttracker.com/markers/anti-dsdna","notice":"Information, not medical advice. Ranges differ between labs, so the range on your own report is the one your result is judged against."}