{"id":"anti-centromere-b","name":"Anti-Centromere B (CENP-B) Antibody","shortName":"Anti-CENP-B","aliases":["Anti-Centromere","Centromere Antibody","Centromere B Antibody","Centromere Protein B Ab","CENP-B Antibody","Centromere Ab","Centromere B Ab","Centromere Antibody, IgG","Anti-Centromere Antibody","Anticentromere Antibodies","Centromere Autoantibodies","Anti-CENP-B"],"abbreviations":["CENP-B","CENP-B Ab"],"loinc":[{"code":"53982-5","primary":true},{"code":"8068-9","primary":false},{"code":"53981-7","primary":false}],"specimen":"serum","units":[{"ucum":"{AI}","display":"AI"}],"referenceRanges":[{"population":"Adults","low":0,"high":1,"unit":"{AI}","unitDisplay":"AI","note":"Quest reports below 1.0 AI as negative, so a result of exactly 1.0 AI is already in the positive range. The scale is assay-specific: ARUP uses a different scale (AU/mL) in which 29 or less is negative, 30 to 40 is equivocal and 41 or more is positive, and the two scales cannot be converted. Use the cutoff and flag printed on your own report.","sources":[{"title":"Centromere B Antibody (test code 16088)","url":"https://testdirectory.questdiagnostics.com/test/test-detail/16088?cc=MASTER","publisher":"Quest Diagnostics"},{"title":"Centromere Antibody, IgG (test 0050714)","url":"https://ltd.aruplab.com/Tests/Pub/0050714","publisher":"ARUP Laboratories"}]}],"review":{"status":"ai-verified","label":"AI-verified against cited sources. Awaiting expert review","lastReviewed":"2026-10-03"},"summary":"Measures antibodies against CENP-B, a protein at the center of chromosomes. They are linked to limited systemic sclerosis (CREST) and, in some people, to primary biliary cholangitis.","url":"https://bloodtesttracker.com/markers/anti-centromere-b","notice":"Information, not medical advice. Ranges differ between labs, so the range on your own report is the one your result is judged against."}