{"id":"alpha-1-globulin-percent","name":"Alpha-1 Globulin, SPEP (percent)","shortName":"Alpha-1 Globulin %","aliases":["Alpha-1 Globulin Percent","Alpha-1 Globulins Percent","A1 Globulin Percent","SPEP Alpha 1 Percent","Alpha-1 Globulin, Percent (SPEP)","Alpha-1 Globulin Fraction Percent","Alpha-1 Globulin (% of Total Protein)","Alpha-1 Globulin Pct"],"abbreviations":[],"loinc":[{"code":"13978-2","primary":true}],"specimen":"serum","units":[{"ucum":"%","display":"%"}],"referenceRanges":[{"population":"Adults","low":2.9,"high":4.9,"unit":"%","unitDisplay":"%","note":"This is the interval in the Sebia Capillarys Protein(E) 6 package insert (2.9-4.9%), as quoted in Table 4 of Bikila et al. 2022. It applies to capillary electrophoresis. A 2023 Spanish hospital paper quotes 3-4% as a typical normal pattern, and the studies in the Bikila table span roughly 2-10%, so labs differ. Bikila's own sex-specific intervals for healthy adults in Addis Ababa (capillary system) were 3.0-5.4% for men and 3.4-5.6% for women. Use the interval printed on your own report first.","sources":[{"title":"Establishment of Reference Intervals for Serum Protein Electrophoresis of Apparently Healthy Adults in Addis Ababa, Ethiopia","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9419900/","publisher":"International Journal of General Medicine","year":2022},{"title":"Utility of the Serum Protein Electrophoresis in the Opportunistic Screening for the Deficiency of Alpha-1 Antitrypsin","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10486943/","publisher":"Diagnostics (Basel)","year":2023}]}],"review":{"status":"ai-verified","label":"AI-verified against cited sources. Awaiting expert review","lastReviewed":"2026-10-03"},"summary":"The share of your serum protein in the alpha-1 zone on electrophoresis, mostly alpha-1 antitrypsin. Reported as a percent of total protein.","url":"https://bloodtesttracker.com/markers/alpha-1-globulin-percent","notice":"Information, not medical advice. Ranges differ between labs, so the range on your own report is the one your result is judged against."}